Overview

Endpoint Preclinical’s Interventional & Minimally Invasive Procedures service offers a comprehensive suite of catheter-based, endoscopic, and hybrid surgical interventions tailored for advanced preclinical research. We deliver a broad range of techniques—from percutaneous device implantation, balloon angioplasty, and laparoscopic procedures to robotic-assisted interventions—that yield reproducible data for complex studies.

Our on-site procedures are executed in your laboratory and are designed to support diverse research models with the precision and efficiency required for complex device and therapeutic studies.

Minimally Invasive and Interventional Services
  • Transcatheter placement
  • Balloon angioplasty
  • Laparoscopic surgery
  • Intravascular imaging
  • Hybrid interventions
Minimally Invasive and Interventional Services
  • Transcatheter placement
  • Balloon angioplasty
  • Laparoscopic surgery
  • Intravascular imaging
  • Hybrid interventions

Service Highlights

Below is a selection of our offerings. If you don’t see exactly what you need, please contact us—we can likely help tailor a solution for your research.

  • Transcatheter Device Implantation: Precise placement of stents, valves, and other devices via catheter-based approaches to support studies in device efficacy and safety.

  • Balloon Angioplasty & Dilatation: Use of balloon techniques to dilate stenotic vessels and prepare access routes for subsequent interventions.

  • Percutaneous Access & Closure: Techniques for vascular access—including sheath insertion and percutaneous closure—critical for minimally invasive studies.

  • Intravascular Imaging & Hemodynamic Assessment: Utilization of intravascular imaging modalities (including Optical Coherence Tomography, OCT) and pressure–volume loop measurements to guide interventions and assess device performance.

  • Electrophysiological Mapping & Ablation: Catheter-based methods for mapping electrical conduction and performing ablation procedures.

  • Transcatheter Valve Interventions: Procedures including transcatheter aortic, mitral, tricuspid, and pulmonary valve replacement or repair to support advanced cardiac models.

  • Laparoscopic & Robotic-Assisted Procedures: Minimally invasive surgical techniques employing laparoscopic and robotic platforms to perform complex interventions with enhanced precision.

  • Hybrid Interventions: Integration of conventional interventional methods with minimally invasive or robotic-assisted approaches to refine and validate complex procedures.

  • Adjunctive Vascular Interventions: Techniques such as drug-coated balloon treatments, stent grafting, and peripheral vascular interventions designed for comprehensive vascular model development.

  • Multi-System Interventions: Development of integrated models that require coordinated interventional procedures across multiple organ systems.

Meet our Surgical Experts!

Sam Gilbert, VMD

Sam Gilbert, VMD

Expert in Advanced Surgical Techniques, Regulatory Strategy, and Medical Device Development. View Profile

Mark Urtz

Mark Urtz, BS

Expert in Interventional Procedures, Study Design, and Medical Device Testing. View Profile

Vince Mendenhall

Vince Mendenhall, DVM, PhD

World-Renowned Surgeon in Cardiovascular, Neurosurgical, and Orthopedic Procedures. View Profile

Dale Groth, BS, SRS

Dale Groth, BS, SRS

Expert in Cardiac, Neurovascular & Vascular Surgery, Advanced Interventional Techniques and Disease Model Development. View Profile

Dale Groth, BS, SRS

Tim Hacker, PhD

Expert in Cardiovascular Models, Advanced Sonography, and Hemodynamic Data Analysis. View Profile

Why Endpoint?

Endpoint Preclinical delivers high-caliber interventional expertise right into your lab, enabling you to test devices, refine techniques, and collect robust data in a controlled setting. We emphasize collaborative study design and advanced imaging support to address complex endpoints, from electrophysiology to stent placement. Whether you’re developing a novel transcatheter device or validating minimally invasive protocols, our specialized approach ensures precise, consistent, and regulator-ready outcomes for your research.

Related Services

Structural Heart

Structural
Heart Procedures

Neuroscience Services

Neurosurgery &
Neurotechnology

Model Development

Model
Development