Overview

Endpoint Preclinical’s General & Reconstructive Surgery service delivers a broad array of open surgical interventions designed for advanced preclinical research. We offer a wide range of techniques—from standard organ resection and kidney transplantation to complex gastrointestinal, abdominal, and soft tissue reconstructive procedures—that yield robust, reproducible data for sophisticated studies.

Our on-site procedures are tailored to diverse research models, reflecting the depth of expertise and comprehensive surgical solutions we provide.

Surgical Services
  • Organ resection models
  • GI & soft tissue surgery
  • Wound healing studies
  • Multi-system modeling
  • Hybrid surgical methods
Surgical Services
  • Organ resection models
  • GI & soft tissue surgery
  • Wound healing studies
  • Multi-system modeling
  • Hybrid surgical methods

Service Highlights

Below is a selection of what we offer. If you don’t see what you’re looking for, please contact us—we can likely help.

  • Organ Resection & Transplantation: Partial or complete organ resection and kidney transplantation procedures designed to create reliable models for therapeutic evaluation and disease simulation.

  • Gastrointestinal & Abdominal Surgery: Techniques including gastric bypass, colorectal resection, and other abdominal interventions that address digestive system research and model development.

  • Soft Tissue & Wound Reconstruction: Methods for wound closure, skin grafts, flap transfers, and other reconstructive techniques aimed at optimizing tissue repair and supporting regenerative studies.

  • General Surgical Repair: Interventions addressing conditions such as urinary incontinence, vasectomy, prostate ablation.

  • Reconstructive Procedures: Multi-stage approaches including free-flap transfers, composite tissue grafts, and multi-vessel reconstructions for comprehensive defect repair and revascularization.

  • Hybrid Techniques: Integration of conventional surgical methods with advanced reconstructive strategies to develop and refine models for challenging clinical scenarios.

  • Multi-System Model Development: Creation of integrated disease models that require coordinated surgical interventions across organ systems—such as combined cardiovascular, renal, and pulmonary procedures—to simulate complex pathological states.

Meet our Surgical Experts!

Dale Groth, BS, SRS

Dale Groth, BS, SRS

Expert in Cardiac, Neurovascular & Vascular Surgery, Advanced Interventional Techniques and Disease Model Development. View Profile

Vince Mendenhall

Vince Mendenhall, DVM, PhD

World-Renowned Surgeon in Cardiovascular, Neurosurgical, and Orthopedic Procedures. View Profile

Sam Gilbert, VMD

Sam Gilbert, VMD

Expert in Advanced Surgical Techniques, Regulatory Strategy, and Medical Device Development. View Profile

Christina Gross

Christina Gross, BA, SRS

Expert in Surgical & Interventional Techniques, Cardiovascular, Transplant, and Reconstructive Procedures. View Profile

Why Endpoint?

Endpoint Preclinical brings decades of cross-specialty expertise to every reconstructive challenge. Whether creating multi-organ disease models or performing delicate reconstructive procedures, we blend technical precision with practical insight into study design. Our on-site approach streamlines workflow and helps your team adapt rapidly to shifting research demands, driving meaningful outcomes in complex surgical scenarios. We focus on delivering reproducible data that accelerates your research trajectory.

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