Overview

Endpoint Preclinical’s Radiology service delivers expert interpretation, scoring review, analysis, and reporting of preclinical imaging data across a broad range of modalities. We transform imaging datasets generated by CROs, pharmaceutical companies, medical device companies, biotechnology teams, and academic research laboratories into scientifically rigorous, decision-ready outputs for both GLP and non-GLP studies, while also providing broader program support across the full imaging workflow.

Our radiology team includes board-certified veterinary radiologists and clinical radiology experts with deep experience spanning cardiac, neurological, oncologic, musculoskeletal, orthopedic, and multi-system disease models.

Radiology Services
  • Board-certified radiology expertise

  • Qualitative & quantitative image review

  • Multimodality imaging interpretation

  • Regulatory-ready reporting

  • End-to-end imaging support

Radiology Services
  • Board-certified radiology expertise

  • Qualitative & quantitative image review

  • Multimodality imaging interpretation

  • Regulatory-ready reporting

  • End-to-end imaging support

Service Highlights

Below is a selection of our offerings. If you don’t see exactly what you need, please contact us. We can tailor our support to your program, infrastructure, and study objectives.

  • Radiology-Based Image Interpretation and Scoring Review: Expert qualitative interpretation grounded in anatomy, physiology, pathology, and study context. Our radiologists perform structured scoring review and adjudication to support standardized assessment frameworks, including ISO-aligned study requirements.

  • Quantitative Imaging Analysis Strategy and Quality Oversight: Design, review, and quality control of quantitative analysis workflows across modalities. We guide region-of-interest definition, atlas development, segmentation strategies, and data validation, particularly for anatomically complex targets and disease models where variability can undermine study conclusions.
  • GLP and Non-GLP Imaging Reporting: Support for imaging results used in exploratory, discovery, IND-enabling, and regulatory-facing studies. Our team contributes methods language, results narratives, scoring rationale, and quality review to ensure imaging outputs are clear, reproducible, and aligned with study expectations.
  • Multimodality Radiology Expertise: Comprehensive support across MRI, PET, SPECT, CT, ultrasound, radiography, and related imaging techniques. Endpoint works with imaging data collected on client, CRO, or academic platforms, providing consistent interpretation regardless of acquisition environment or equipment manufacturer.
  • Radiopharmaceutical and Biodistribution Interpretation: Expert review of imaging- and gamma counting-based biodistribution studies supporting radioligand therapy, oncology, neuroscience, and gene therapy programs. We integrate qualitative findings with quantitative outputs and translational context to strengthen downstream interpretation and decision-making.
  • Imaging Study Design and Modality Consultation: Upstream consulting to support modality selection, acquisition planning, endpoint definition, and scoring strategy. We collaborate with your team to ensure imaging data collection is optimized for scientific relevance, reproducibility, and downstream analysis before studies begin.
  • Therapeutic and Device Area Support: Radiology expertise spanning cardiac and structural heart disease, neurology and neurodegeneration, oncology and radioligand therapy, orthopedics and musculoskeletal research, spinal and peripheral nerve models, pulmonary and respiratory studies, and complex multi-system disease models for both therapeutic and device development programs.

Meet our Preclinical Imaging Experts!

Dr. Howard Dobson

Howard Dobson, BVM&S, DVSc, Dip. ACVR

Expert in Veterinary Radiology, Advanced Data Analysis, Interpretation & Report Generation. View Profile

Derek Cissell, VMD, PhD, DACVR

Expert in Multimodal Imaging, Radiopharmaceutical Biodistribution & Radiology Interpretation. View Profile

Why Endpoint?

Across imaging programs, variability often comes from inconsistent interpretation, unclear scoring criteria, or analysis workflows that are not aligned with study objectives. Endpoint Preclinical reduces this risk by embedding highly experienced radiologists directly into your team and applying structured, standardized approaches to interpretation and reporting.

We strengthen existing imaging workflows with expert oversight, defensible scoring review, and integrated interpretation that supports confident decisions in both ISO-aligned device studies and therapeutic development programs.

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