Ramzi began his research career investigating cardiac metabolism and the cellular processes associated with muscle dysfunction. His doctoral and postdoctoral work expanded that foundation into skeletal and cardiac muscle physiology, including research on muscular dystrophy, mitochondrial calcium dynamics, and cellular signaling. This work contributed to an extensive publication record and helped establish the scientific approach he later brought to independent research and therapeutic development.

In 2014, Ramzi co-founded Myologica, a specialized research organization focused on evaluating neuromuscular function and therapeutic responses. Through Myologica, he has developed capabilities that allow researchers to examine muscle performance at multiple levels, from whole-body movement and coordination to individual muscle contractility. These approaches help distinguish changes in general motor performance from effects on muscle function itself, providing a more complete understanding of treatment responses.

An important part of Ramzi’s work is selecting the appropriate experimental approach for each scientific question. Behavioral assessments can help characterize overall performance, while in vivo, in situ, and ex vivo techniques allow researchers to investigate specific aspects of muscle strength, fatigue, contractility, and injury susceptibility. By integrating these complementary methods, he helps research teams determine whether observed changes reflect meaningful improvements in muscle function and identify the physiological mechanisms behind those effects.