Dr. Brad Bolon is a globally recognized expert in toxicologic neuropathology and neuroanatomical interpretation, with over 30 years of experience supporting preclinical research in academia, government, and industry. He is widely known for his pioneering work in identifying and characterizing macroscopic and microscopic findings in CNS (brain and spinal cord) and PNS (ganglia and nerves) neural tissues across a broad range of nonclinical species and disease models. At Endpoint, Brad provides focused consulting in study design, data acquisition and interpretation, and pathology peer review to clients working in discovery and development of neuroactive products including small molecules, biomolecules, cell and gene therapies, and medical devices.

Brad offers specialized expertise in approaches to neural tissue sampling and evaluation, providing remote support for data interpretation, pathology reporting, and manuscript development. A prolific speaker and author, Brad is widely regarded as a thought leader in his field and has contributed to hundreds of publications, consensus documents, and conference proceedings in a range of fields.

• Neuropathology & Animal Disease Modeling: Evaluates CNS and PNS tissues across a range of research models to support phenotypic characterization in discovery programs.
• Toxicologic Neuropathology Interpretation & Peer Review: Renowned for acquisition and interpretation of microscopic findings in CNS and PNS tissues for conventional and specialized safety studies; frequently engaged for focused neuropathology peer review.
• Neural Tissue Sampling Strategy: Advises on collection and preparation techniques  for brain, spinal cord, ganglia and nerve tissues in specialized nonclinical studies.
• Technical Report & Manuscript Preparation and Editing: As warranted, generates or provides detailed editing of anatomic pathology reports and contributes to co-authored scientific manuscripts that meet publication standards for multiple tiers of basic and applied science journals.
• Training & Scientific Mentorship: Supports internal teams with guidance on neuroanatomy and histological interpretation, helping researchers strengthen their understanding of neural tissue analysis.

Brad’s consulting practice is grounded in scientific integrity and providing a meaningful impact by helping to accelerate the development of novel treatments for severe and life-threatening neurological diseases. Focused and purposeful, Brad frequently works on the most specialized projects—bringing accuracy, precision and decades of broad biological knowledge to every engagement.

Experimental Design
Data Acquisition
Data Interpretation
Report Generation
Technical Manuscript Preparation

Light Microscopy (Brightfield & Fluorescence)
Neuropathological Grading Systems
Pathology Peer Review (conventional and digital)
Photodocumentation & Annotation Tools