Overview

Endpoint Preclinical’s Microsurgery service is built for precision and comprehensive application in preclinical research. We offer a broad spectrum of surgical techniques—from detailed microvascular and nerve reconstructions in various research models to complex, multi-system reconstructive procedures—designed to yield robust, reproducible data for complex studies.

Our procedures are tailored to meet the rigorous demands of research while delivering consistency and reliability in every intervention.

Microsurgery
  • Microvascular repair
  • Intrathecal drug delivery
  • Complex reconstructions
  • Telemetry integration
  • Multi-system models
Microsurgery
  • Microvascular repair
  • Intrathecal drug delivery
  • Complex reconstructions
  • Telemetry integration
  • Multi-system models

Service Highlights

Below is a selection of our offerings. If you don’t see exactly what you need, please contact us—we can likely help tailor a solution for your research.

  • Microvascular Anastomoses: End-to-end, side-to-side, and end-to-side vessel connections that restore flow and support studies in ischemia, tissue engineering, and device validation.

  • Nerve Repair & Grafting: Detailed nerve repairs and graft implantations designed to restore neural function and evaluate regenerative therapies.

  • Intrathecal & Intracerebroventricular Access: Targeted catheterization for drug delivery or fluid sampling in central nervous system research.

  • Telemetry Integration: Implantation of a range of telemetric devices from various providers across diverse research models.

  • Model Development: Establishment of reproducible disease models in cardiac, renal, pulmonary, neuro, and other systems tailored to specific study objectives.

  • Advanced Reconstructive Procedures: Free-flap transfers, composite tissue grafts, and multi-vessel reconstructions for comprehensive defect repair and revascularization.

  • Hybrid Neurosurgical Approaches: Integration of microsurgical techniques with minimally invasive or robotic-assisted methods for complex cranial and spinal interventions, including decompression and dural repair.

  • Organ-Level Reconstruction: Partial organ resection, revascularization, and grafting procedures executed with meticulous microsurgical suturing.

  • Multi-System Model Development: Development of integrated disease models requiring simultaneous microsurgical interventions across cardiovascular, neurological, and orthopedic systems.

Meet our Microsurgery Experts!

Yelena Akelina

Yelena Akelina, DVM, MS

Expert in Advanced Microsurgery, Model Development, and Precision Training. View Profile

Tim Hacker, PhD

Tim Hacker, PhD

Expert in Cardiovascular Models, Advanced Sonography, and Hemodynamic Data Analysis. View Profile

Oliver Wearing, PhD

Oliver Wearing, PhD

Expert in Cardiovascular Physiology & Preclinical Microsurgery. View Profile

Eric Adams

Eric Adams, MS, SRS

Expert in Neurosurgical Interventions, Preclinical Research, and Targeted Drug Delivery. View Profile

Vince Mendenhall

Vince Mendenhall, DVM, PhD

World-Renowned Surgeon in Cardiovascular, Neurosurgical, and Orthopedic Procedures. View Profile

Sam Gilbert, VMD

Sam Gilbert, VMD

Expert in Advanced Surgical Techniques, Regulatory Strategy, and Medical Device Development. View Profile

Christina Gross

Christina Gross, BA, SRS

Expert in Surgical & Interventional Techniques, Cardiovascular, Transplant, and Reconstructive Procedures. View Profile

Why Endpoint?

Endpoint Preclinical excels at blending technical microsurgical skill with the rigorous demands of preclinical study design. Our specialists collaborate closely with your team to refine protocols, integrate advanced imaging or telemetry, and ensure consistent data capture across disease models. By working seamlessly in your own lab environment, we help you push the limits of what’s possible in microsurgery—accelerating discoveries and reducing variability in challenging interventions.

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