A trailblazer in preclinical surgery, Dr. Mendenhall brings over 50 years of experience in cardiovascular, neurosurgical, and orthopedic procedures.

Endpoint Preclinical is honored to welcome Dr. Vince Mendenhall, DVM, Ph.D., to our Expert Network. Dr. Mendenhall’s career spans five decades and encompasses a profound impact on preclinical research, including the establishment of surgical techniques and study designs that have shaped modern investigative surgery. A pioneer in his field, Dr. Mendenhall has performed tens of thousands of surgeries, with his contributions recognized by the Academy of Surgical Research, which established the Vince Mendenhall Award in his honor. View Vince’s Profile

Dr. Mendenhall is renowned for his expertise in cardiovascular, neurosurgical, and orthopedic surgery. His technical capabilities include:

• Arterio-Venous Fistulas and Valve Placement: Complex vascular surgeries for device testing and therapeutic development.
• Telemetry Implantations and Catheterizations: Long-term physiological monitoring and pharmacokinetic studies.
• Craniectomy and Laminectomy: Techniques for neurological research and spinal cord injury models.
• Bile Duct Cannulation: Specialized procedures for first-pass pharmacokinetics and lymphatic studies.

Surgical Planning and Reporting: Dr. Mendenhall offers expertise in reviewing detailed surgical protocols aligned with GLP standards, assisting study directors, and reviewing reports for regulatory submissions, including those required by the FDA.

Regulatory and Histopathological Insights: With proficiency in ISO-10993-6 and ASTM standards, Dr. Mendenhall ensures rigorous compliance in all aspects of study design and execution. His understanding of histopathological endpoints provides valuable interpretations for surgical outcomes.

As a mentor to over a thousand researchers and surgical technicians, Dr. Mendenhall has dedicated his career to advancing the skills of others. His programs emphasize aseptic technique, ethical research practices, and the application of advanced surgical methods. His leadership roles, including presidency of the Academy of Surgical Research, further reflect his commitment to education and innovation in the field.

Dr. Mendenhall’s contributions span numerous research areas, including:

• Cardiovascular and Neurological Disorders: Developing models for device testing and therapeutic exploration.
• Orthopedic Surgery: Advancing techniques for tendon repair, bone grafting, and vertebral reconstructions.
• Targeted Drug Delivery: Expertise in specialized delivery systems such as intrathecal and bile duct administration.

Join us in welcoming Dr. Vince Mendenhall to Endpoint Preclinical. His unparalleled expertise in preclinical surgery and regulatory compliance enhances our ability to deliver innovative solutions for clients worldwide. Contact us to learn how Dr. Mendenhall can support your research needs.