Tim Hacker, PhD
Expert in Cardiovascular Models, Advanced Sonography, and Hemodynamic Data Analysis
Tim Hacker, PhD
Expert in Cardiovascular Models, Advanced Sonography, and Hemodynamic Data Analysis
Professional Summary
Dr. Tim Hacker is a prominent figure in preclinical cardiovascular research, with over 30 years of experience in developing and studying animal models of cardiac disease. Utilizing advanced surgical and microsurgical techniques, Dr. Hacker provides clients with both surgical and data collection services directly in their labs. He also leads Endpoint Preclinical’s rodent sonography program, specializing in echocardiography data collection, analysis, and interpretation. Known for his expertise in cardiovascular hemodynamics, particularly ventricular pressure-volume (PV) loops, Dr. Hacker routinely collaborates with industry and academic clients. His innovations have contributed directly to regulatory filings, successful clinical trials, and hundreds of publications.
Core Competencies
- Cardiovascular Research Expertise:
Extensive experience developing preclinical models of cardiac disease, with a focus on myocardial infarction, pressure overload, pulmonary hypertension, and heart failure. Specializes in functional assessments of the cardiac and pulmonary systems. - Surgical & Microsurgical Procedures:
Performed tens of thousands of cardiovascular surgeries, including myocardial infarctions, aortic and pulmonary banding, vascular catheterization, and telemetry implantation. Highly skilled in catheter-based procedures like ventricular pressure-volume (PV) loops. - Advanced Sonography:
Expert in capturing and analyzing echocardiography data, including ventricular performance, valve function, and blood flow. Specialized in advanced imaging for complex models such as HFpEF, HFrEF, pulmonary hypertension, hypertrophic cardiomyopathy, and many others. - Data Analysis & Interpretation:
Highly skilled in collecting, analyzing, and interpreting complex datasets, particularly in ultrasound imaging and ventricular pressure-volume loops. This expertise has supported hundreds of successful studies and regulatory filings. - Training & Mentorship:
With over 25 years of experience leading a core lab, Tim has trained and mentored hundreds of researchers in advanced surgical techniques, imaging, and data collection. Training has defined Tim’s career and plays a central role in his consulting.
Personal Philosophy
Tim’s philosophy focuses on bridging preclinical research with clinical applications through meticulous experimental design, innovative data collection, and collaborative teamwork. He is available to lead projects, teach specialized techniques, and review your data, both in your lab and remotely.